Geographers have devised different ways to divide Colombia into regions. It is most appropriate to divide the country into four geographic regions: the Andean highlands, consisting of the three Andean ranges and intervening valley lowlands; the Caribbean lowlands coastal region; the Pacific lowlands coastal region, separated from the Caribbean lowlands by swamps at the base of the Isthmus of Panama; and eastern Colombia, the great plain that lies to the east of the Andes Mountains.

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Source: U.S. Library of Congress